ethyl 3-hydrazino-3-oxopropionate
ethyl 3-hydrazino-3-oxopropionate
CAS: 30866-24-1
Molecular Formula: C5H10N2O3
ethyl 3-hydrazino-3-oxopropionate - Names and Identifiers
| Name | ethyl 3-hydrazino-3-oxopropionate |
| Synonyms | Nsc75205 N1-Ethylmalonohydrazide ETHYL MALONYL HYDRAZIDE Ethyl malonyl hydrazide Ethyl malonyl hydrazine ethyl 3-hydrazino-3-oxopropionate ETHYL 3-HYDRAZINO-3-OXOPROPIONATE Ethyl 3-oxo-3-hydrazino-propionate ethyl 3-hydrazinyl-3-oxopropanoate |
| CAS | 30866-24-1 |
| InChI | InChI=1/C5H10N2O3/c1-2-10-5(9)3-4(8)7-6/h2-3,6H2,1H3,(H,7,8) |
| InChIKey | HCPOCMMGKBZWSJ-UHFFFAOYSA-N |
ethyl 3-hydrazino-3-oxopropionate - Physico-chemical Properties
| Molecular Formula | C5H10N2O3 |
| Molar Mass | 146.14 |
| Density | 1.176±0.06 g/cm3(Predicted) |
| Melting Point | 72-75 °C (lit.) |
| Boling Point | 320.9±25.0 °C(Predicted) |
| Flash Point | 147.8°C |
| Vapor Presure | 0.000309mmHg at 25°C |
| pKa | 12.02±0.35(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.462 |
ethyl 3-hydrazino-3-oxopropionate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
ethyl 3-hydrazino-3-oxopropionate - Introduction
ethyl 3-hydrazino-3-oxopropionate, chemical formula C5H10N2O3, molecular weight of 146.15g/mol, is an organic compound. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
-Appearance: ethyl 3-hydrazino-3-oxopropionate is a colorless to slightly yellow liquid.
-Solubility: It can be dissolved in water and some organic solvents, such as methanol and ethanol.
-Stability: The compound is relatively stable at room temperature.
Use:
-Synthesis intermediate: ethyl 3-hydrazino-3-oxopropionate can be used as an important intermediate in organic synthesis and used to synthesize other compounds.
-Pharmaceutical research: Due to its hydrazine and carboxyl groups, this compound has potential application value in the field of pharmaceutical research.
Method:
The preparation of ethyl 3-hydrazino-3-oxopropionate can be carried out by the following steps:
1. The ethyl ester and 3-oxoacetone are condensed in the presence of a base.
2. The resulting product was reacted with hydrazine in acetic acid.
Safety Information:
There is little safety information about ethyl 3-hydrazino-3-oxopropionate, so general laboratory safety regulations should be followed when using and handling it. Specific safety information, such as toxicity and hazard information is not available, please read the relevant literature and safety data sheets carefully before use.
Nature:
-Appearance: ethyl 3-hydrazino-3-oxopropionate is a colorless to slightly yellow liquid.
-Solubility: It can be dissolved in water and some organic solvents, such as methanol and ethanol.
-Stability: The compound is relatively stable at room temperature.
Use:
-Synthesis intermediate: ethyl 3-hydrazino-3-oxopropionate can be used as an important intermediate in organic synthesis and used to synthesize other compounds.
-Pharmaceutical research: Due to its hydrazine and carboxyl groups, this compound has potential application value in the field of pharmaceutical research.
Method:
The preparation of ethyl 3-hydrazino-3-oxopropionate can be carried out by the following steps:
1. The ethyl ester and 3-oxoacetone are condensed in the presence of a base.
2. The resulting product was reacted with hydrazine in acetic acid.
Safety Information:
There is little safety information about ethyl 3-hydrazino-3-oxopropionate, so general laboratory safety regulations should be followed when using and handling it. Specific safety information, such as toxicity and hazard information is not available, please read the relevant literature and safety data sheets carefully before use.
Last Update：2024-04-09 21:54:55
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CAS: 30866-24-1
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CAS: 30866-24-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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